Transgenics & Other Animal Services

Transgenics & Other Animal Services

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Transgenics & Other Animal Services

Core Facilities Transgenics and Animals Code

Penn State College of Medicine offers accredited services in the generation of transgenic and knockout mice and in rederivation. The College is also home to a zebrafish facility (opened in 2016) and a pulmonary immunology and physiology facility (opened in 2015).

The laboratory animal medicine programs at Penn State College of Medicine are accredited through a number of major organizations, including AAALAC International, AALAS, ACLAM, ASLAP, AAVMC and PSBR.


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Core Facilities Zebrafish Tab Code

Zebrafish Functional Genomics Core

The Zebrafish Functional Genomics Core at Penn State College of Medicine was established to provide the Penn State research community with a modern, centralized facility for housing, breeding and performing experiments with zebrafish, one of the fastest growing model systems in biomedical research, as well as the intellectual infrastructure to do that work.

About the Facility

The Zebrafish Functional Genomics Core is a newly designed facility housing a state-of-the-art Pentair Aquatic Habitats recirculating aquaria, housed in the Department of Comparative Medicine.

The central housing room is equipped with 32 racks of recirculating aquaria, able to accommodate any combination of 1, 3 and 10 liter tanks.

Other facilities include twin 16-rack recirculating systems with independent filtration/purification, an isolated quarantine room with three stand-alone housing systems, a sentinel pathogen-monitoring program, a procedure room and three independently controlled light-tight breeding cabinets.

See photos of the facility taken during its April 2016 grand opening.

This image of the Zebrafish Functional Genomics Core at Penn State College of Medicine, taken during its April 2016 grand opening, shows an aisle framed by five shelves of zebrafish tanks down either side. The tanks appear deep blue, and zebrafish can faintly be seen swimming in the frontmost ones.
Penn State College of Medicine's Zebrafish Functional Genomics Core opened in April 2016.


The Zebrafish Functional Genomics Core provides a variety of instrumentation for microinjection and fluorescence imaging.


  • Eppendorf FemtoJet microinjectors
  • Manual micromanipulators
  • ZEISS Stereo Discovery.V8 microscopes

Fluorescence Imaging

  • Leica MZ FLIII Fluorescence Stereomicroscope
  • Olympus MVX10 MacroView Macro Zoom Fluorescence Microscope
  • ZEISS Axio Zoom.V16 Zoom Fluorescence Microscope with ZEISS ApoTome.2


Fish are available to both Penn State College of Medicine and external investigators. We currently house the following wild type lines: AB, Conner, Ekkwill, Liles, Tübingen (Tu) and WIK. We also house a selection of mutant and transgenic lines.

Contact Us

For details on the Zebrafish Functional Genomics Core, email Khai Chung Ang, PhD, Scientific Director, at or call 717-531-4704.