Research in Molecular and Precision Medicine

Cancer biology

• DNA repair and enhancing therapeutic effectiveness of DNA damaging agents

• Genomic biomarkers of disease for non-invasive detection of cancer

• Genomics of melanoma

• Synthesis of novel therapeutic molecules

• Natural product prevention of head and neck cancer

• The role of human papilloma virus in head and neck cancer

Structural Biology

• Cryo-electron microscopy of proteins and neurons

• Development of advanced nuclear magnetic resonance-based structure determination and its application to membrane proteins involved in cancer progression

Genetic and Epigenetic Basis of Disease

• X inactivation and X-linked genes associated with female biased diseases, such as bleeding disorders and autoimmune disease (multiple sclerosis and lupus)

• Structure determination of repressive chromatin, regulation of its formation and its role on neuronal development and retinal blindness

The Microbiome

• Identifying the spectrum of microbes in the gut and the effect of diet on their composition

• The correlation between the microbiome and human health