Research Projects

Photo: Left, fracture callus. Right, Fracture callus single-cell RNA sequence.

Bone, Joint and Implant Biomechanics

• R01-funded project: Computer simulation development for surgeon training in fracture fixation biomechanics

• R25-funded research education program: device design for biomedical engineering undergraduates

• Collaboration with surgeons on industry-supported implant biomechanics studies

Photos: Top, patient-specific modeling of two options for femur fracture fixation (with fracture occurring between hip and knee joint replacements). Bottom, mechanical testing of a cadaver with shoulder replacement.

Tendon Remodeling

• Degeneration (NSF CAREER, NIH R21)

• Repair (DOD)

• Development (NSF, NIH R21)

A left side titled Structure-Function and a right side titled Mechanobiology with two curved arrows in the center indicating a cyclical or interactive process between the sections. The structure-function section has multiscale testing with a heat map image, microscopic imaging with an imaging taken from a microscope and modeling with a diagram labeled unit cell depicted with a diagram labeled Unit Cell. The Mechanobiology has three microscopic images titled Mechanical Stimuli, Gene Expression and protein Synthesis.