Mass Spectrometry & Proteomics

Mass Spectrometry & Proteomics

Penn State College of Medicine's Mass Spectrometry & Proteomics Core provides mass spectrometry analyses and identification of proteins, peptides, oligonucleotides, carbohydrates and small molecules.

Other services include separations of complex protein and/or peptide mixtures; protein expression analysis (iTraq, SILAC, SWATH/DIA label-free); quantitation of protein, cytokine, amino acid and other small-molecule levels; bioinformatics; spot-cutting and robotics; and gel imaging and analysis.

Instrumentation

The following major equipment is available in the Mass Spectrometry & Proteomics Core:

  • ABSciex TripleTOF 5600+ Mass Spec
  • ABI/MDS Sciex 5800 MALDI TOF-TOF Mass Spec
  • MDS Sciex 4000 QTrap Hybrid Ion Trap Mass Spec
  • Waters Synapt HDMS Hybrid QTOF with Ion Mobility
  • ABI Voyager DE-PRO Reflectron MALDI TOF Mass Spec
  • MesoScale Discoveries (MSD) Sector Imager 2400 Electrochemiluminescence Detector/Plate Reader
  • HPLC/UPLC and Gel Separation Systems
  • Gel Imaging and Analysis Tools
  • Spot-Cutting and Robotics
  • Shimadzu CHiP Printer
  • Wyatt DAWN HELEOS Light-Scattering Detection System (for protein sizing)
  • Biacore 3000 Surface Plasmon Resonance System

Contact Us

For details on the Mass Spectrometry & Proteomics Core, email Bruce Stanley, Director, at bstanley@psu.edu or call 717-531-5329.